Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Deba_2573Protein of unknown function DUF1998; InterPro IPR018973; KEGG: sfu:Sfum_3851 hypothetical protein; PFAM: Protein of unknown function DUF1998; SPTR: A0LQ18 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1998). (615 aa)    
Predicted Functional Partners:
Deba_2571
ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: sfu:Sfum_3853 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; SPTR: A0LQ20 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 
 0.957
Deba_2574
Helicase domain protein; InterPro IPR001650; KEGG: sfu:Sfum_3850 helicase domain-containing protein; PFAM: helicase domain protein; SMART: helicase domain protein; SPTR: A0LQ17 Helicase domain protein; PFAM: Helicase conserved C-terminal domain.
 
     0.955
Deba_2572
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: sfu:Sfum_3852 phospholipase D/transphosphatidylase; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: A0LQ19 Phospholipase D/Transphosphatidylase.
 
     0.950
Deba_2577
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
 
 
 
 0.916
Deba_2575
Hypothetical protein; InterPro IPR002052:IPR002296; KEGG: sfu:Sfum_3847 hypothetical protein; SPTR: A0LQ14 Putative uncharacterized protein.
 
     0.881
Deba_2578
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525:IPR018117; KEGG: sfu:Sfum_3845 DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: A0LQ12 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
  
 0.879
Deba_2570
DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
     0.774
Deba_2579
Phage transcriptional regulator, AlpA; InterPro IPR010093:IPR009061:IPR010260; KEGG: sfu:Sfum_3844 phage transcriptional regulator, AlpA; PFAM: Prophage CP4-57 regulatory; SPTR: A0LQ11 Phage transcriptional regulator, AlpA; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Prophage CP4-57 regulatory protein (AlpA); TIGRFAM: DNA binding domain, excisionase family.
 
     0.695
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
   
 
 0.540
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
     
 0.483
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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