STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2643Protein of unknown function DUF1998; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterProIPR014001:IPR001650:IPR012337:IPR011545:IPR 018973:IPR014021; KEGG: sfu:Sfum_1698 DEAD/DEAH box helicase domain-containing protein; PFAM: Protein of unknown function DUF1998; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LIY3 DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DE [...] (963 aa)    
Predicted Functional Partners:
Deba_2642
Protein of unknown function DUF89; COGs: COG1578 conserved hypothetical protein; InterPro IPR002791:IPR014444; KEGG: dau:Daud_1372 hypothetical protein; PFAM: protein of unknown function DUF89; SPTR: B1I472 Putative uncharacterized protein; PFAM: Protein of unknown function DUF89.
       0.773
Deba_2640
Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: mta:Moth_0135 Appr-1-p processing; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: A0A021 Putative uncharacterized protein; PFAM: Macro domain.
       0.686
Deba_2641
MltA domain protein; COGs: COG2821 Membrane-bound lytic murein transglycosylase; InterPro IPR005300:IPR010611; KEGG: sat:SYN_02860 membrane-bound lytic murein transglycosylase; PFAM: MltA domain protein; 3D domain protein; SPTR: Q2LSX7 Membrane-bound lytic murein transglycosylase; PFAM: MltA specific insert domain; 3D domain.
       0.661
Deba_2577
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
     
 0.635
Deba_2644
Fe-S cluster domain protein; COGs: COG4871 conserved hypothetical protein; InterPro IPR007202; KEGG: sfu:Sfum_3600 Fe-S cluster domain-containing protein; PFAM: Fe-S cluster domain protein; SPTR: A0LPB8 Fe-S cluster domain protein; PFAM: Putative Fe-S cluster.
       0.555
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.545
Deba_0272
COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: dsa:Desal_1067 single-stranded nucleic acid binding R3H domain protein; PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; SPTR: C6C0J7 Single-stranded nucleic acid binding R3H domain protein; PFAM: R3H domain.
  
   
 0.412
Deba_0094
Conserved hypothetical protein; COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; InterPro IPR004209; KEGG: dol:Dole_2967 hypothetical protein; SPTR: A8ZYZ7 Putative uncharacterized protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain.
  
     0.408
Deba_3067
KEGG: sfu:Sfum_0040 hypothetical protein; SPTR: A0LE91 Putative uncharacterized protein.
  
     0.402
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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