STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2658DEAD/DEAH box helicase domain protein; COGs: COG1200 RecG-like helicase; InterProIPR014001:IPR001650:IPR016027:IPR004365:IPR 011545:IPR014021; KEGG: gbm:Gbem_1903 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: B5EB56 ATP-dependent DNA helicase RecG; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG. (702 aa)    
Predicted Functional Partners:
Deba_2659
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR015421:IPR015422:IPR015424:IPR000653; KEGG: rca:Rcas_0781 glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Q1NSW9 DegT/DnrJ/EryC1/StrS aminotransferase:Aromatic amino acid beta-eliminating lyase/threonine aldolase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
       0.746
Deba_0352
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.637
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.633
Deba_1106
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 
 0.605
Deba_0111
Hypothetical protein; KEGG: eic:NT01EI_1130 outer membrane usher protein FimD, putative; SPTR: B8A6Z1 Putative uncharacterized protein.
   
  
 0.595
Deba_1720
Bifunctional DNA primase/polymerase; InterPro IPR015330:IPR000276; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.
   
  
 0.595
Deba_2241
Bifunctional DNA primase/polymerase; InterPro IPR015330; KEGG: apt:APA01_26890 DNA recombinase RecA; PFAM: Bifunctional DNA primase/polymerase; SPTR: C6N3S3 Putative truncated Phage / plasmid primase P4; PFAM: Bifunctional DNA primase/polymerase, N-terminal.
   
  
 0.595
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
     0.594
Deba_3024
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: dal:Dalk_2782 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: B8FKV2 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
     
 0.594
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
     0.580
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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