STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2677Beta-lactamase domain protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: adg:Adeg_1793 beta-lactamase domain protein; SPTR: C9R9A2 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily. (274 aa)    
Predicted Functional Partners:
Deba_0763
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.911
Deba_0393
Beta-lactamase; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: rpd:RPD_2374 beta-lactamase-like; SPTR: Q137Y3 Beta-lactamase-like; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
Deba_1872
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: xac:XAC1784 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: B7A5Y7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFA [...]
     
  0.900
Deba_2675
Protein of unknown function UPF0066; COGs: COG1720 conserved hypothetical protein; InterPro IPR001378:IPR002177; KEGG: mla:Mlab_1087 sodium-transporting two-sector ATPase; PFAM: protein of unknown function UPF0066; SPTR: A2SSF0 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: conserved hypothetical protein TIGR00104.
 
     0.820
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.775
Deba_2676
InterPro IPR001497; KEGG: sfu:Sfum_2405 hypothetical protein; SPTR: A0LKY4 Conserved hypothetical cytosolic protein.
       0.773
Deba_2678
PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR014729:IPR011063:IPR012089; KEGG: sfu:Sfum_1613 PP-loop domain-containing protein; PFAM: PP-loop domain protein; SPTR: A0LIP8 PP-loop domain protein; PFAM: PP-loop family; Belongs to the TtcA family.
       0.773
Deba_2176
Cobyrinic acid ac-diamide synthase; COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR017896:IPR017900:IPR002586:IPR001450; KEGG: sfu:Sfum_3409 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LNT0 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; 4Fe-4S binding domain.
 
     0.713
Deba_2175
Cobyrinic acid ac-diamide synthase; COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR017896:IPR017900:IPR002586:IPR001450; KEGG: sfu:Sfum_3408 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LNS9 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
     0.699
Deba_2674
InterPro IPR015391:IPR000297; KEGG: dat:HRM2_18710 PpiD1; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; SPTR: C0QBW0 PpiD1; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain.
       0.645
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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