STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2695Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR016055:IPR005844:IPR005845:IPR 005846:IPR005843:IPR005841; KEGG: sfu:Sfum_0481 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; SPTR: A0LFH9 Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] (451 aa)    
Predicted Functional Partners:
Deba_2698
Nucleotidyl transferase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538; KEGG: sat:SYN_01031 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; SPTR: Q2LSE4 Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
 
 0.980
Deba_2696
COGs: COG1482 Phosphomannose isomerase; InterPro IPR014710:IPR011051:IPR001250:IPR014628; KEGG: dge:Dgeo_0321 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Q1J1L0 Mannose-6-phosphate isomerase; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
  
 
 0.973
Deba_2690
COGs: COG0058 Glucan phosphorylase; InterPro IPR011834:IPR000811; KEGG: dba:Dbac_2874 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: C7LUN4 Alpha-glucan phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
 
 
 0.971
Deba_0808
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011004:IPR005835:IPR018357; KEGG: ank:AnaeK_3750 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: B4UE03 Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
  
 
 0.953
Deba_0121
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR016066:IPR005852; KEGG: gur:Gura_2654 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: A5G4W1 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: [...]
  
0.948
glgC
Nucleotidyl transferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.945
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.936
Deba_2290
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.933
Deba_0224
Transketolase; COGs: COG0021 Transketolase; InterProIPR005474:IPR005475:IPR005476:IPR009014:IPR 005478:IPR015941; KEGG: pna:Pnap_4499 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: A6C7Q1 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 0.929
Deba_0396
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: gbm:Gbem_1326 ROK family protein; PFAM: ROK family protein; SPTR: B5EI81 ROK family protein; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
  
 
 0.926
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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