STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2715Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: sfu:Sfum_2119 signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; SPTR: A0LK50 Signal peptide peptidase A. Serine peptidase. MEROPS family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. (300 aa)    
Predicted Functional Partners:
Deba_2716
Protein of unknown function DUF540; COGs: COG2981 Uncharacterized protein involved in cysteine biosynthesis; InterPro IPR007496; KEGG: rrs:RoseRS_3441 hypothetical protein; PFAM: protein of unknown function DUF540; SPTR: A5UYU6 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF540).
       0.789
Deba_2714
Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
     
 0.737
Deba_2717
Hypothetical protein; KEGG: psb:Psyr_3722 amino acid adenylation; SPTR: Q4ZQ18 Amino acid adenylation.
       0.693
Deba_3097
Tetratricopeptide TPR_2 repeat protein; InterProIPR001440:IPR013105:IPR019734:IPR013026:IPR 011990; KEGG: dat:HRM2_20780 tetratricopeptide (TPR) domain protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SPTR: C0QDB3 Tetratricopeptide (TPR) domain protein; PFAM: ChAPs (Chs5p-Arf1p-binding proteins); TIGRFAM: putative PEP-CTERM system TPR-repeat lipoprotein.
  
 
 0.526
Deba_3150
KEGG: nph:NP2780A hypothetical protein; SPTR: C0EZ14 Putative uncharacterized protein; PFAM: Bacterial membrane flanked domain.
   
    0.521
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: gbm:Gbem_3257 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: C8R0Z9 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
       0.496
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR005861:IPR001917:IPR015421:IPR015422:IPR 015424:IPR004839; KEGG: sfu:Sfum_2116 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A0LK47 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.491
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.486
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
       0.480
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.471
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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