STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2745COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644:IPR013785; KEGG: dvm:DvMF_2848 CBS domain containing membrane protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: B8DRE8 CBS domain containing membrane protein; PFAM: CBS domain. (222 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.827
purE
Phosphoribosylamine/glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.
  
  
 0.624
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.586
Deba_0693
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR004099:IPR016156:IPR013027:IPR000815:IPR 012999; KEGG: rxy:Rxyl_1767 mercuric reductase MerA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: B4D639 Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
   
   0.580
Deba_2198
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR016156:IPR013027:IPR000815:IPR004099:IPR 012999:IPR006258; KEGG: dsa:Desal_3027 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C6C0Y2 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
   0.580
Deba_2981
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR004099:IPR000815:IPR016156:IPR 012999:IPR006258; KEGG: mta:Moth_1763 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: A1HU83 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
   0.580
Deba_2571
ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: sfu:Sfum_3853 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; SPTR: A0LQ20 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 0.533
flgK
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR001444:IPR010810:IPR010930; KEGG: dal:Dalk_0987 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellin hook IN repeat protein; flagellar basal body rod protein; SPTR: B8FK15 Flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
   
   0.522
Deba_2200
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR016156:IPR001763:IPR013027:IPR004099; KEGG: dps:DP0550 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: Q6AQU4 Related to NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
  
 
 
 0.516
Deba_2746
Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001:IPR006555:IPR014013:IPR001650; KEGG: noc:Noc_1364 helicase C2; SMART: helicase c2; DEAD-like helicase; SPTR: Q3JBD8 Helicase c2; PFAM: DEAD_2; DEAD/DEAH box helicase.
       0.506
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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