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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Deba_2774COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331:IPR000408; KEGG: ade:Adeh_4279 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: Q2IHI5 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (372 aa)    
Predicted Functional Partners:
Deba_1022
UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR016040:IPR003869:IPR020025; KEGG: dsa:Desal_3630 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; SPTR: C6BTJ5 Polysaccharide biosynthesis protein CapD; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase.
  
 
 0.951
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
 0.923
Deba_0291
COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR001228; KEGG: ppd:Ppro_0501 UDP-N-acetylglucosamine pyrophosphorylase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: A1ALB2 Bifunctional protein glmU; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase.
    
 0.921
Deba_0395
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterProIPR001732:IPR014026:IPR014027:IPR008927:IPR 016040:IPR017476; KEGG: dal:Dalk_1698 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: B8FEJ1 Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mann [...]
 
  
 0.920
Deba_2290
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.857
Deba_2698
Nucleotidyl transferase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538; KEGG: sat:SYN_01031 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; SPTR: Q2LSE4 Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
    
 0.850
Deba_0808
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011004:IPR005835:IPR018357; KEGG: ank:AnaeK_3750 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: B4UE03 Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
    
 0.843
lpxA
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
  0.815
Deba_1678
Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797:IPR002229; KEGG: gbm:Gbem_1791 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: B5EAA1 Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.783
Deba_2421
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR016040:IPR011004:IPR000683:IPR001451; KEGG: cbc:CbuK_0696 NAD-dependent oxidoreductase; PFAM: oxidoreductase domain protein; transferase hexapeptide repeat containing protein; SPTR: B6J6Q3 NAD-dependent oxidoreductase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Bacterial transferase hexapeptide (three repeats).
 
  
 0.780
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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