Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2778Metal dependent phosphohydrolase; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607:IPR006675; KEGG: dal:Dalk_0653 metal dependent phosphohydrolase; PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: C8QWH2 Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG. (283 aa)    
Predicted Functional Partners:
cheD-2
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.790
Deba_2780
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
       0.787
Deba_2776
KEGG: dat:HRM2_34450 hypothetical protein; SPTR: C0Q915 Putative uncharacterized protein.
       0.727
Deba_2777
COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR011006; KEGG: sat:SYN_00967 chemotaxis protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q2LSK7 Chemotaxis protein; PFAM: Response regulator receiver domain.
       0.722
Deba_3074
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR011006:IPR001789; KEGG: dma:DMR_39840 putative response regulator; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: C4XNX4 Putative response regulator; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
      0.689
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.609
Deba_2781
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: sus:Acid_5368 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Q01VJ8 CheW protein; PFAM: CheW-like domain.
       0.597
Deba_2774
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331:IPR000408; KEGG: ade:Adeh_4279 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: Q2IHI5 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
       0.591
Deba_2357
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: slo:Shew_2040 diguanylate cyclase; PFAM: GGDEF domain containing protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; SPTR: A3QEK8 Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
      0.575
Deba_2286
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: amc:MADE_03704 GGDEF domain protein; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; SPTR: A3WMD3 Phytochrome sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
      0.547
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.