Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2782CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 005467:IPR004358:IPR009082; KEGG: dal:Dalk_0656 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: Q1NT42 CheW-like protein:ATP-binding region, ATPase-like:Signal transducing histidine kinase, homodime [...] (780 aa)    
Predicted Functional Partners:
Deba_2781
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: sus:Acid_5368 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Q01VJ8 CheW protein; PFAM: CheW-like domain.
 
 0.998
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.997
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.996
Deba_2843
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dal:Dalk_2352 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: B8FAV9 CheW protein; PFAM: CheW-like domain.
 
 0.995
Deba_1255
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: dde:Dde_0384 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: C0GLF0 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 0.992
Deba_3007
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004090:IPR016160; KEGG: dal:Dalk_4960 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: B8FHJ1 Methyl-accepting chemotaxis sensory transducer; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.985
Deba_2777
COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR011006; KEGG: sat:SYN_00967 chemotaxis protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q2LSK7 Chemotaxis protein; PFAM: Response regulator receiver domain.
 
 0.980
Deba_0164
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: dal:Dalk_2351 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: Q1NVV5 Chemotaxis sensory transducer; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.977
Deba_0485
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004090:IPR018212; KEGG: dba:Dbac_1917 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: C0GS91 Methyl-accepting chemotaxis sensory transducer; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.977
Deba_0538
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dde:Dde_1077 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Q313L8 Methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.977
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.