Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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Deba_2846COGs: COG1882 Pyruvate-formate lyase; InterPro IPR004184; KEGG: dal:Dalk_4867 formate C-acetyltransferase; PFAM: pyruvate formate-lyase PFL; PRIAM: Formate C-acetyltransferase; SPTR: B8FDB2 Formate C-acetyltransferase; PFAM: Pyruvate formate lyase. (720 aa)    
Predicted Functional Partners:
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
  
  
 0.763
Deba_0189
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197; KEGG: ppd:Ppro_1469 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: A1AP15 Radical SAM domain protein; PFAM: Periplasmic binding protein; Radical SAM superfamily.
  
  
 0.690
Deba_0699
Anaerobic ribonucleoside-triphosphate reductase activating protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012840:IPR007197; KEGG: pvi:Cvib_0808 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; SPTR: Q1PZG6 Similar to ribonucleoside triphosphate reductase activating protein NrdG; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein.
  
  
 0.690
Deba_2898
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR016431; KEGG: dma:DMR_15300 hypothetical protein; PFAM: Radical SAM domain protein; SPTR: C4XNP6 Putative uncharacterized protein; PFAM: Radical SAM superfamily.
  
  
 0.690
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
  
 0.603
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.550
Deba_2844
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR013656:IPR002078:IPR002197:IPR 000014:IPR003593:IPR020441:IPR011006:IPR009057; KEGG: gsu:GSU2506 sensory box protein/sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: response regulator receiver; PAS domain containing protein; AAA ATPase; SPTR: Q74A84 S [...]
     
 0.530
Deba_2845
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003661:IPR003594:IPR000014:IPR 005467:IPR004358:IPR009082; KEGG: gsu:GSU1038 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q74EC5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His [...]
     
 0.530
Deba_1380
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.529
Deba_0261
COGs: COG0778 Nitroreductase; InterPro IPR001450:IPR000415:IPR017896:IPR017900; KEGG: dol:Dole_1688 nitroreductase; PFAM: nitroreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A9A0J2 Nitroreductase; PFAM: Nitroreductase family.
 
  
 0.517
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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