Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2856COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003594:IPR000014:IPR 001610:IPR005467:IPR000700:IPR004358; KEGG: aba:Acid345_0692 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Q1ITV3 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. (758 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 
0.972
Deba_0403
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR003661:IPR 003594:IPR011006:IPR009082:IPR000014:IPR001610:IPR004358:I PR005467:IPR000700; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region [...]
 
 
0.926
Deba_1323
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700:IPR004358:IPR003018:I PR001610:IPR011006:IPR009082; KEGG: dal:Dalk_0107 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; GAF domain protein; PAC repeat-containing protein; response [...]
 
 
0.918
Deba_2154
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR011006:IPR001789; KEGG: dal:Dalk_3262 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FJ25 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 
 0.882
Deba_0602
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: sat:SYN_01292 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q2LX20 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Response regulator receiver domain.
 
 
 
 0.881
Deba_2017
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: lip:LI1142 CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q1MP81 CheY-like receiver; PFAM: Response regulator receiver domain.
 
 
 
 0.875
Deba_0630
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR011006:IPR009082:IPR004358:IPR013656:I PR013767; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; re [...]
 
 
0.840
Deba_1066
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867:IPR018480; KEGG: sfu:Sfum_0707 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: A0LG53 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 
 0.838
Deba_0019
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR011006:IPR009082:IPR019825:I PR004358; KEGG: dal:Dalk_2518 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; response regulator recei [...]
 
 
0.837
Deba_1225
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.832
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.