STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2858COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR018062; KEGG: pth:PTH_2271 xanthine/uracil permeases; PFAM: Xanthine/uracil/vitamin C permease; SPTR: A5CZY9 Xanthine/uracil permeases; PFAM: Permease family; TIGRFAM: uracil-xanthine permease. (570 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.938
Deba_2480
Anti-sigma-factor antagonist; InterPro IPR003658:IPR002645; KEGG: sfu:Sfum_1506 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: A0LIE3 Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
 
 0.857
Deba_0154
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: swo:Swol_1795 anti-anti-sigma regulatory factor, SpoIIAA; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q0AW11 Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.840
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.839
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterProIPR002082:IPR006130:IPR019825:IPR006132:IPR 006131; KEGG: dol:Dole_0514 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: A8ZU12 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: as [...]
  
  
 0.834
purE
Phosphoribosylamine/glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.
  
  
 0.829
Deba_2322
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR013325:IPR013324:IPR000943:IPR011991:IPR 007627:IPR007624:IPR007630:IPR014284:IPR012845; KEGG: mgm:Mmc1_3037 FliA/WhiG family RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; SPTR: A0LC35 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; S [...]
  
 
 0.822
Deba_1234
Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q1NPE5 Sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.808
Deba_2233
Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: hmo:HM1_0319 anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q1NPE5 Sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
 
 0.808
Deba_3182
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR004010:IPR003660:IPR010822:IPR001932; KEGG: dma:DMR_08680 putative phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C4XK04 Putative phosphatase; PFAM: HAMP domain; Cache domain; Stage II sporulation protein E (SpoIIE).
 
 
 0.805
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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