| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Deba_0282 | Deba_2866 | Deba_0282 | Deba_2866 | Protein of unknown function DUF583; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: mxa:MXAN_7475 hypothetical protein; PFAM: protein of unknown function DUF583; SPTR: Q1CVJ5 Putative uncharacterized protein; PFAM: Protein of unknown function, DUF583. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.518 |
| Deba_1176 | Deba_2744 | Deba_1176 | Deba_2744 | Penicillin-binding protein 1C; COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterProIPR012338:IPR001264:IPR001460:IPR009647:IPR 011815; KEGG: ade:Adeh_2036 glycosyl transferase family penicillin-binding protein transpeptidase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Q2IJH6 Glycosyl transferase, family 51 / Penicillin-binding protein, transpeptidase; TIGRFAM: penicillin-binding protein 1C; PFAM: Penicillin-Binding Protein C-terminus Fami [...] | Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR012338:IPR011816; KEGG: dol:Dole_2534 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: A8ZWA4 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. | 0.933 |
| Deba_1176 | Deba_2866 | Deba_1176 | Deba_2866 | Penicillin-binding protein 1C; COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterProIPR012338:IPR001264:IPR001460:IPR009647:IPR 011815; KEGG: ade:Adeh_2036 glycosyl transferase family penicillin-binding protein transpeptidase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Q2IJH6 Glycosyl transferase, family 51 / Penicillin-binding protein, transpeptidase; TIGRFAM: penicillin-binding protein 1C; PFAM: Penicillin-Binding Protein C-terminus Fami [...] | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.487 |
| Deba_1302 | Deba_1771 | Deba_1302 | Deba_1771 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.600 |
| Deba_1302 | Deba_2278 | Deba_1302 | Deba_2278 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | COGs: COG0681 Signal peptidase I; InterProIPR015927:IPR000223:IPR011056:IPR019756:IPR 019757:IPR019758:IPR019759; KEGG: dvm:DvMF_2718 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: B8DIZ6 Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | 0.598 |
| Deba_1302 | Deba_2744 | Deba_1302 | Deba_2744 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR012338:IPR011816; KEGG: dol:Dole_2534 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: A8ZWA4 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. | 0.490 |
| Deba_1302 | Deba_2866 | Deba_1302 | Deba_2866 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.525 |
| Deba_1771 | Deba_1302 | Deba_1771 | Deba_1302 | Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | 0.600 |
| Deba_1771 | Deba_2866 | Deba_1771 | Deba_2866 | Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.563 |
| Deba_2278 | Deba_1302 | Deba_2278 | Deba_1302 | COGs: COG0681 Signal peptidase I; InterProIPR015927:IPR000223:IPR011056:IPR019756:IPR 019757:IPR019758:IPR019759; KEGG: dvm:DvMF_2718 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: B8DIZ6 Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | 0.598 |
| Deba_2278 | Deba_2866 | Deba_2278 | Deba_2866 | COGs: COG0681 Signal peptidase I; InterProIPR015927:IPR000223:IPR011056:IPR019756:IPR 019757:IPR019758:IPR019759; KEGG: dvm:DvMF_2718 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: B8DIZ6 Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.598 |
| Deba_2278 | secA | Deba_2278 | Deba_2868 | COGs: COG0681 Signal peptidase I; InterProIPR015927:IPR000223:IPR011056:IPR019756:IPR 019757:IPR019758:IPR019759; KEGG: dvm:DvMF_2718 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: B8DIZ6 Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.483 |
| Deba_2744 | Deba_1176 | Deba_2744 | Deba_1176 | Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR012338:IPR011816; KEGG: dol:Dole_2534 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: A8ZWA4 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. | Penicillin-binding protein 1C; COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterProIPR012338:IPR001264:IPR001460:IPR009647:IPR 011815; KEGG: ade:Adeh_2036 glycosyl transferase family penicillin-binding protein transpeptidase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Q2IJH6 Glycosyl transferase, family 51 / Penicillin-binding protein, transpeptidase; TIGRFAM: penicillin-binding protein 1C; PFAM: Penicillin-Binding Protein C-terminus Fami [...] | 0.933 |
| Deba_2744 | Deba_1302 | Deba_2744 | Deba_1302 | Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR012338:IPR011816; KEGG: dol:Dole_2534 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: A8ZWA4 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. | 0.490 |
| Deba_2744 | Deba_2866 | Deba_2744 | Deba_2866 | Penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR012338:IPR011816; KEGG: dol:Dole_2534 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: A8ZWA4 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.675 |
| Deba_2864 | Deba_2865 | Deba_2864 | Deba_2865 | GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182:IPR016181; KEGG: sfu:Sfum_1203 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A0LHJ4 N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family. | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510:IPR008263; KEGG: gme:Gmet_0947 peptidase U62, modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: C6MMK6 Peptidase U62 modulator of DNA gyrase; PFAM: Putative modulator of DNA gyrase. | 0.785 |
| Deba_2864 | Deba_2866 | Deba_2864 | Deba_2866 | GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182:IPR016181; KEGG: sfu:Sfum_1203 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A0LHJ4 N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.498 |
| Deba_2864 | secA | Deba_2864 | Deba_2868 | GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182:IPR016181; KEGG: sfu:Sfum_1203 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A0LHJ4 N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.460 |
| Deba_2865 | Deba_2864 | Deba_2865 | Deba_2864 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510:IPR008263; KEGG: gme:Gmet_0947 peptidase U62, modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: C6MMK6 Peptidase U62 modulator of DNA gyrase; PFAM: Putative modulator of DNA gyrase. | GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182:IPR016181; KEGG: sfu:Sfum_1203 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A0LHJ4 N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family. | 0.785 |
| Deba_2865 | Deba_2866 | Deba_2865 | Deba_2866 | Peptidase U62 modulator of DNA gyrase; COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510:IPR008263; KEGG: gme:Gmet_0947 peptidase U62, modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: C6MMK6 Peptidase U62 modulator of DNA gyrase; PFAM: Putative modulator of DNA gyrase. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: dol:Dole_2484 peptidase M23B; PFAM: Peptidase M23; SPTR: A8ZW54 Peptidase M23B; PFAM: Peptidase family M23. | 0.501 |