Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_2887NUDIX hydrolase; COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086:IPR015797:IPR020084; KEGG: ote:Oter_2376 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: C1ZKP1 Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. (165 aa)    
Predicted Functional Partners:
Deba_1928
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092:IPR008949; KEGG: gsu:GSU1765 geranyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Q74CA9 Geranyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.927
Deba_3133
Short-chain dehydrogenase/reductase SDR; COGs: COG3425 3-hydroxy-3-methylglutaryl CoA synthase; InterProIPR016040:IPR016039:IPR016083:IPR013747:IPR 002878:IPR002198:IPR003033:IPR002347; KEGG: dol:Dole_1550 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; protein of unknown function DUF35; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Sterol-binding domain protein; SPTR: A8ZZV4 Short-chain dehydrogenase/reductase SDR; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C term [...]
  
  
 0.846
Deba_2888
Hypothetical protein; KEGG: asa:ASA_0300 membrane carboxypeptidase; SPTR: A4SHW2 Membrane carboxypeptidase.
       0.773
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
    0.766
Deba_0461
Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR010523:IPR004096:IPR002078:IPR002197:IPR 009057:IPR003593:IPR020441; KEGG: dal:Dalk_3884 sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; 4-vinyl reductase 4VR; Activator of aromatic catabolism; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: B8FCF2 Sigma54 specific transcriptional regulator, Fis family; PFAM: Activator of aromatic catabolism; Bacterial r [...]
  
    0.562
Deba_2889
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753:IPR018376; KEGG: bpt:Bpet4719 enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: A9IFN7 Enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.553
Deba_2890
COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: rpt:Rpal_1911 nitroreductase; PFAM: nitroreductase; SPTR: C3RWW2 Putative nitroreductase; PFAM: Nitroreductase family.
       0.540
Deba_1272
COGs: COG5345 conserved hypothetical protein; InterPro IPR016936; KEGG: kko:Kkor_0593 hypothetical protein; PFAM: Uncharacterised conserved protein UCP029693; SPTR: C0N6C1 Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2333).
  
    0.526
Deba_2209
Geranylgeranyl reductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR003042:IPR006076:IPR011777; KEGG: mta:Moth_0808 geranylgeranyl reductase; PFAM: FAD dependent oxidoreductase; SPTR: Q2RKB3 Geranylgeranyl reductase; TIGRFAM: geranylgeranyl reductase; PFAM: FAD dependent oxidoreductase; TIGRFAM: geranylgeranyl reductase family.
  
  
 0.469
Deba_3038
Lycopene beta and epsilon cyclase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR008671:IPR003042; KEGG: afr:AFE_2544 geranylgeranyl reductase family protein; PFAM: Lycopene beta and epsilon cyclase; SPTR: B7J778 Geranylgeranyl reductase family protein; PFAM: HI0933-like protein.
  
  
 0.469
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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