STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2956MT-A70 family protein; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757:IPR002052; KEGG: rde:RD1_1079 DNA methyltransferase; PFAM: MT-A70 family protein; SPTR: C8S3H4 MT-A70 family protein; PFAM: MT-A70; Belongs to the MT-A70-like family. (217 aa)    
Predicted Functional Partners:
Deba_2957
Restriction endonuclease BglII; InterPro IPR015278; KEGG: ajs:Ajs_0427 hypothetical protein; PFAM: Restriction endonuclease BglII; SPTR: C8R2M4 Restriction endonuclease BglII; PFAM: Restriction endonuclease BglII.
 
     0.929
Deba_1598
InterPro IPR006935:IPR018187; KEGG: dau:Daud_0199 type III restriction enzyme, res subunit; PFAM: type III restriction protein res subunit; SPTR: B1I0R5 Type III restriction enzyme, res subunit; manually curated; PFAM: Type III restriction enzyme, res subunit.
  
     0.532
Deba_1599
DNA methylase N-4/N-6 domain protein; COGs: COG2189 Adenine specific DNA methylase Mod; InterPro IPR002941:IPR002295:IPR002052:IPR005829; KEGG: sfu:Sfum_2856 DNA methylase N-4/N-6 domain-containing protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: A0LM81 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase.
  
     0.519
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
   0.512
Deba_0107
Putative phage repressor; COGs: COG2932 transcriptional regulator protein; InterProIPR001387:IPR019759:IPR015927:IPR010982:IPR 011056; KEGG: csa:Csal_1365 putative phage repressor; PFAM: helix-turn-helix domain protein; Peptidase S24/S26A/S26B, conserved region; SMART: helix-turn-helix domain protein; SPTR: Q1QXT8 Putative phage repressor; PFAM: Helix-turn-helix; Peptidase S24-like.
  
    0.474
Deba_1312
Transcriptional regulator, XRE family; InterPro IPR001387:IPR015927:IPR010982; KEGG: dvm:DvMF_1678 putative phage repressor; SMART: helix-turn-helix domain protein; SPTR: B8DLY0 Putative phage repressor.
  
    0.474
Deba_1611
Putative phage repressor; InterProIPR001387:IPR015927:IPR010982:IPR019759:IPR 011056; KEGG: csa:Csal_1365 putative phage repressor; PFAM: helix-turn-helix domain protein; Peptidase S24/S26A/S26B, conserved region; SMART: helix-turn-helix domain protein; SPTR: Q1QXT8 Putative phage repressor; PFAM: Helix-turn-helix; Peptidase S24-like.
  
    0.454
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
  0.401
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.