STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Deba_2960MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: dde:Dde_2418 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Q30YN1 MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family. (457 aa)    
Predicted Functional Partners:
Deba_0537
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020828:IPR020829:IPR020831:IPR016040:IPR 020832:IPR006424:IPR020830; KEGG: sfu:Sfum_1468 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: A0LIA5 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehyd [...]
  
  
 0.811
Deba_2714
Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
    0.776
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
 
 0.706
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.651
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR012340:IPR 020825:IPR005147:IPR016027:IPR009061:IPR005146; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: A0LFC7 Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synth [...]
     
 0.532
Deba_2961
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR001638:IPR013656:IPR013767:IPR000160:IPR 001633:IPR000014:IPR001610:IPR000700; KEGG: mei:Msip34_1854 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein fam [...]
  
    0.530
Deba_0528
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: dma:DMR_22930 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: C4XSU2 Putative ABC transporter ATP-binding protein; PFAM: ABC transporter.
  
  
 0.455
Deba_2465
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439:IPR015851; KEGG: pth:PTH_1476 ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: A5D288 ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit.
  
  
 0.455
Deba_2962
Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: hap:HAPS_0507 multiple antibiotic resistance (MarC)-related protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: A3VDE1 Putative uncharacterized protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427.
     
 0.451
Deba_3222
Type I phosphodiesterase/nucleotide pyrophosphatase; COGs: COG3379 conserved hypothetical protein; InterPro IPR017850:IPR002591:IPR017849; KEGG: dvu:DVU0155 type I phosphodiesterase/nucleotide pyrophosphatase family protein; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Q72FQ8 Type I phosphodiesterase/nucleotide pyrophosphatase family protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.445
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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