STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_2973Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647:IPR012287:IPR009057:IPR011075; KEGG: dal:Dalk_1395 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: B8F9Z9 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family. (219 aa)    
Predicted Functional Partners:
Deba_2974
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR016040:IPR002347; KEGG: dal:Dalk_1396 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: B8FA00 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
     
 0.704
Deba_3193
Transcriptional regulator, TetR family; InterPro IPR009057:IPR011075:IPR001647:IPR012287; KEGG: dal:Dalk_1849 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: B8FFZ1 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.537
Deba_2975
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR016196; KEGG: mei:Msip34_1770 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: C6X6M2 Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
     
 0.499
Deba_1782
InterPro IPR009057:IPR001647:IPR012287; KEGG: mpt:Mpe_A2962 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: C5SCW5 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.472
Deba_2976
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterProIPR013154:IPR013149:IPR011032:IPR016040:IPR 002328:IPR000169; KEGG: rec:RHECIAT_CH0003132 probable L-iditol 2-dehydrogenase protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: B7RXG2 Alcohol dehydrogenase GroES-like domain family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
     
 0.451
Deba_2977
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.442
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
   
 
 0.435
Deba_0968
Transcriptional regulator, TetR family; InterPro IPR001647:IPR009057:IPR012287; KEGG: dat:HRM2_21660 HTH-type transcriptional regulator; PFAM: regulatory protein TetR; SPTR: C0QDK0 HTH-type transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.434
Deba_2877
COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931; KEGG: dal:Dalk_0469 transglutaminase domain protein; PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; SPTR: B8FH88 Transglutaminase domain protein; PFAM: Transglutaminase-like superfamily.
  
     0.426
Deba_2978
Dehydrogenase E1 component; COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017:IPR018370; KEGG: rxy:Rxyl_0348 pyruvate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component; SPTR: B7S016 Dehydrogenase E1 component superfamily protein; PFAM: Dehydrogenase E1 component.
     
 0.410
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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