STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_2976Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterProIPR013154:IPR013149:IPR011032:IPR016040:IPR 002328:IPR000169; KEGG: rec:RHECIAT_CH0003132 probable L-iditol 2-dehydrogenase protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: B7RXG2 Alcohol dehydrogenase GroES-like domain family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (340 aa)    
Predicted Functional Partners:
Deba_1113
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198:IPR016040; KEGG: dal:Dalk_2964 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: B8FL19 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
 
 
 0.930
Deba_0343
COGs: COG3527 Alpha-acetolactate decarboxylase; InterPro IPR005128; KEGG: pth:PTH_2358 alpha-acetolactate decarboxylase; PFAM: alpha-acetolactate decarboxylase; PRIAM: Acetolactate decarboxylase; SPTR: Q1JWS4 Acetolactate decarboxylase; TIGRFAM: alpha-acetolactate decarboxylase; PFAM: Alpha-acetolactate decarboxylase; TIGRFAM: alpha-acetolactate decarboxylase.
     
 0.914
Deba_2977
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.809
Deba_2978
Dehydrogenase E1 component; COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017:IPR018370; KEGG: rxy:Rxyl_0348 pyruvate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component; SPTR: B7S016 Dehydrogenase E1 component superfamily protein; PFAM: Dehydrogenase E1 component.
 
  
 0.805
Deba_2979
Transketolase domain protein; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR005475:IPR005476:IPR015941:IPR009014:IPR 013838; KEGG: sso:SSO1526 pyruvate dehydrogenase beta subunit (lipoamide); PFAM: Transketolase domain protein; Transketolase central region; SPTR: B7S015 Transketolase, C-terminal domain protein; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
  
 0.779
Deba_2980
Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089:IPR004167:IPR001078:IPR011053:IPR 003016; KEGG: rha:RHA1_ro11029 dihydrolipoyllysine-residue succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Q0RVL0 Dihydrolipoyllysine-residue succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 bi [...]
 
  
 0.751
Deba_2975
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR016196; KEGG: mei:Msip34_1770 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: C6X6M2 Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
  
  
 0.711
lipB-2
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.672
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
  
 
 0.666
Deba_2974
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR016040:IPR002347; KEGG: dal:Dalk_1396 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: B8FA00 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
 
  
 0.632
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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