STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Deba_2977ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (337 aa)    
Predicted Functional Partners:
Deba_2978
Dehydrogenase E1 component; COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017:IPR018370; KEGG: rxy:Rxyl_0348 pyruvate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component; SPTR: B7S016 Dehydrogenase E1 component superfamily protein; PFAM: Dehydrogenase E1 component.
 
  
 0.906
Deba_2979
Transketolase domain protein; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR005475:IPR005476:IPR015941:IPR009014:IPR 013838; KEGG: sso:SSO1526 pyruvate dehydrogenase beta subunit (lipoamide); PFAM: Transketolase domain protein; Transketolase central region; SPTR: B7S015 Transketolase, C-terminal domain protein; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
  
 0.874
Deba_2980
Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089:IPR004167:IPR001078:IPR011053:IPR 003016; KEGG: rha:RHA1_ro11029 dihydrolipoyllysine-residue succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Q0RVL0 Dihydrolipoyllysine-residue succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 bi [...]
 
  
 0.861
Deba_2976
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterProIPR013154:IPR013149:IPR011032:IPR016040:IPR 002328:IPR000169; KEGG: rec:RHECIAT_CH0003132 probable L-iditol 2-dehydrogenase protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: B7RXG2 Alcohol dehydrogenase GroES-like domain family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
  
  
 0.809
lipB-2
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
 
     0.786
Deba_2975
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR016196; KEGG: mei:Msip34_1770 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: C6X6M2 Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
       0.689
Deba_2986
COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR000923; KEGG: tro:trd_0142 hypothetical protein; PFAM: biotin/lipoate A/B protein ligase; SPTR: A8UQP5 Putative uncharacterized protein; PFAM: Bacterial lipoate protein ligase C-terminus; Biotin/lipoate A/B protein ligase family.
 
     0.594
Deba_2983
Hypothetical protein; InterPro IPR011031; KEGG: sat:SYN_02638 iron-sulphur-binding reductase; SPTR: C8QXC7 Cytochrome C family protein; TIGRFAM: doubled CXXCH domain.
 
     0.580
Deba_2981
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR004099:IPR000815:IPR016156:IPR 012999:IPR006258; KEGG: mta:Moth_1763 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: A1HU83 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
 
   
 0.578
Deba_2985
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR001450:IPR004017:IPR012285:IPR017896:IPR 009051:IPR017900; KEGG: mac:MA0688 heterodisulfide reductase, subunit D; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q8TSV7 CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D; PFAM: Cysteine-rich domain.
 
     0.507
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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