Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_3004Antibiotic biosynthesis monooxygenase; COGs: COG1359 conserved hypothetical protein; InterPro IPR007138:IPR011008; KEGG: ppd:Ppro_0311 antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: A1AKS5 Antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase. (97 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
    0.526
Deba_3005
KEGG: hypothetical protein LOC607637; SPTR: Q6H5R0 Putative uncharacterized protein OJ1031_C12.24.
       0.512
Deba_3003
Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: tai:Taci_1748 transcriptional regulator, BadM/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: D1B7H1 Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator).
  
    0.492
Deba_3002
InterPro IPR001450:IPR017896; KEGG: dal:Dalk_2338 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FAU5 4Fe-4S ferredoxin iron-sulfur binding domain protein.
       0.475
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.472
Deba_3000
Metal dependent phosphohydrolase; InterPro IPR006674:IPR003607:IPR006675; KEGG: dal:Dalk_2340 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: B8FAU7 Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
       0.464
Deba_1507
Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: hch:HCH_04623 sugar (pentulose and hexulose) kinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Q2SDF1 Sugar (Pentulose and hexulose) kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain.
  
  
 0.450
Deba_3001
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR006067:IPR001450:IPR017896:IPR017900; KEGG: dal:Dalk_2339 nitrite and sulphite reductase 4Fe-4S region; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; nitrite and sulphite reductase 4Fe-4S region; SPTR: B8FAU6 Nitrite and sulphite reductase 4Fe-4S region; PFAM: 4Fe-4S binding domain; Nitrite and sulphite reductase 4Fe-4S domain.
       0.448
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.435
Deba_3006
KEGG: dps:DP2299 hypothetical protein; SPTR: Q6AKU7 Putative uncharacterized protein.
       0.431
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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