STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_3036Radical SAM domain protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR007197:IPR013785:IPR006638; KEGG: mta:Moth_0445 radical SAM family protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q2RLB3 Radical SAM; PFAM: Radical SAM superfamily. (347 aa)    
Predicted Functional Partners:
Deba_3037
Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; InterPro IPR007197:IPR013785:IPR006638; KEGG: mta:Moth_0446 radical SAM family protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q2RLB2 Radical SAM.
 
   
 0.957
Deba_3039
COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR002829; KEGG: mta:Moth_0443 biotin/lipoate A/B protein ligase; PFAM: biotin/lipoate A/B protein ligase; protein of unknown function DUF116; SPTR: Q2RLB5 Biotin/lipoate A/B protein ligase; PFAM: Protein of unknown function DUF116; Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoyltransferase and lipoate-protein ligase.
 
     0.949
Deba_3038
Lycopene beta and epsilon cyclase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR008671:IPR003042; KEGG: afr:AFE_2544 geranylgeranyl reductase family protein; PFAM: Lycopene beta and epsilon cyclase; SPTR: B7J778 Geranylgeranyl reductase family protein; PFAM: HI0933-like protein.
 
     0.912
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
  0.900
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
  0.900
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
     
  0.900
Deba_3040
COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR011053:IPR002930:IPR003016; KEGG: mta:Moth_0438 glycine cleavage system H protein; PFAM: glycine cleavage H-protein; SPTR: Q2RLC0 Glycine cleavage system H protein; PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein.
 
   
 0.849
Deba_3041
COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterPro IPR015424:IPR002129:IPR015421; KEGG: dal:Dalk_0154 pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: B8FMJ7 Pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain.
       0.773
Deba_2986
COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR000923; KEGG: tro:trd_0142 hypothetical protein; PFAM: biotin/lipoate A/B protein ligase; SPTR: A8UQP5 Putative uncharacterized protein; PFAM: Bacterial lipoate protein ligase C-terminus; Biotin/lipoate A/B protein ligase family.
 
     0.752
Deba_3035
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: pca:Pcar_1355 putative methyl-accepting chemotaxis protein (MCP); PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Q1JZ62 Methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
       0.468
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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