Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Deba_3051COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_3272 AMP-binding domain protein; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FJ35 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (548 aa)    
Predicted Functional Partners:
Deba_3050
Transcriptional regulator, XRE family; InterPro IPR011051:IPR010982:IPR001387:IPR013096; KEGG: drt:Dret_1668 transcriptional regulator, XRE family; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: C8X3F5 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix.
 
    0.865
Deba_3052
Hypothetical protein; KEGG: pph:Ppha_0360 putative PAS/PAC sensor protein; SPTR: B4SCA9 Putative PAS/PAC sensor protein.
     
 0.714
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.582
Deba_3227
COGs: COG0778 Nitroreductase; InterPro IPR000415:IPR001450:IPR017896:IPR017900; KEGG: dma:DMR_23050 nitroreductase family protein; PFAM: nitroreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C4XSV4 Nitroreductase family protein; PFAM: Nitroreductase family; 4Fe-4S binding domain.
  
 
 0.569
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.562
Deba_3049
D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D-al anine-endopeptidase; COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667:IPR012338; KEGG: mac:MA1969 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Q8TPE4 Serine-type D-Ala-D-Ala carboxypeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family.
       0.499
Deba_1941
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.494
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.492
Deba_3200
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR016040:IPR002198:IPR002347; KEGG: dol:Dole_1475 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: A8ZZC6 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.491
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.477
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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