STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_3057RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterProIPR014284:IPR013325:IPR013324:IPR007627:IPR 013249; KEGG: dma:DMR_42310 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: C4XQ23 RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family. (209 aa)    
Predicted Functional Partners:
Deba_3059
KEGG: sfu:Sfum_3122 hypothetical protein; SPTR: A0LMZ3 Putative uncharacterized protein.
       0.790
Deba_3058
KEGG: jan:Jann_0748 16S rRNA-processing protein RimM; SPTR: Q28UE7 Ribosome maturation factor rimM.
       0.773
Deba_0177
KEGG: mta:Moth_2363 putative transmembrane transcriptional regulator (anti-sigma factor); SPTR: Q2RFZ4 Putative transmembrane transcriptional regulator (Anti-sigma factor).
  
 
 0.767
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.741
Deba_0178
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterProIPR007627:IPR013249:IPR013325:IPR013324:IPR 014284; KEGG: sfu:Sfum_0272 fis family transcriptional regulator; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: A0LEX1 Transcriptional regulator, Fis family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.734
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.711
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.688
Deba_3055
Hypothetical protein; KEGG: CTF1; cardiotrophin 1; K05422 cardiotrophin 1; SPTR: Q5U5Y7 Cardiotrophin 1.
       0.668
Deba_3056
KEGG: psa:PST_2453 hypothetical protein; SPTR: A4VMA4 Putative uncharacterized protein.
       0.668
Deba_3054
SH3 type 3 domain protein; InterPro IPR013247:IPR003646; KEGG: dba:Dbac_0627 SH3 type 3 domain protein; PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; SPTR: Q1K4G2 SH3, type 3; PFAM: Bacterial SH3 domain.
  
  
 0.635
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.