STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speE-2Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (304 aa)    
Predicted Functional Partners:
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
 0.999
Deba_0052
Agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR020855:IPR005925; KEGG: mgm:Mmc1_3564 putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: C8R0F8 Agmatinase; TIGRFAM: agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family.
  
 
 0.949
mtaD
Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
   
  0.913
Deba_0376
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680:IPR011059; KEGG: sat:SYN_01991 chlorohydrolase/deaminase family protein; PFAM: amidohydrolase; SPTR: Q2LUH4 5-methylthioadenosine/S-adenosylhomocysteine deaminase 2; PFAM: Amidohydrolase family.
   
  0.913
Deba_2312
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001543:IPR001689; KEGG: dma:DMR_22580 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: C4XSQ7 Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
    
   0.736
Deba_0143
Arginine decarboxylase, pyruvoyl-dependent; COGs: COG1945 conserved hypothetical protein; InterPro IPR002724:IPR016104; KEGG: aba:Acid345_1944 pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Q1IQA5 Arginine decarboxylase; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent.
  
 
 0.599
mtnA
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
  
 0.524
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.491
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
    0.487
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
   
    0.485
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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