STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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Deba_3160Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (586 aa)    
Predicted Functional Partners:
rsmI
Phosphocarrier, HPr family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
 
 0.995
Deba_1963
Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178:IPR016152; KEGG: sfu:Sfum_2067 putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: A0LJZ8 Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.843
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.794
Deba_3162
Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: dau:Daud_0666 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B1I2N7 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252.
       0.771
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.771
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.771
Deba_1965
COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: gur:Gura_2967 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: A5G5S1 PTS system fructose subfamily IIA component; PFAM: PTS system fructose IIA component.
 
  
 0.721
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
    0.599
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
    0.592
Deba_2953
COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795:IPR004161:IPR004160:IPR009001:IPR 009000:IPR004541:IPR005225; KEGG: dal:Dalk_1928 elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain protein; SPTR: B8FET7 Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU.
   
    0.592
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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