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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Deba_3160Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (586 aa)    
Predicted Functional Partners:
rsmI
Phosphocarrier, HPr family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
 
 0.994
Deba_1963
Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178:IPR016152; KEGG: sfu:Sfum_2067 putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: A0LJZ8 Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.883
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
  
 0.827
Deba_3162
Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: dau:Daud_0666 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B1I2N7 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252.
       0.796
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.796
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.796
Deba_1965
COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: gur:Gura_2967 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: A5G5S1 PTS system fructose subfamily IIA component; PFAM: PTS system fructose IIA component.
 
  
 0.746
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
    0.647
Deba_3167
Conserved hypothetical protein; COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR009019:IPR004088; KEGG: dal:Dalk_4648 hypothetical protein; SPTR: B8FNP5 Putative uncharacterized protein; Belongs to the UPF0109 family.
  
    0.624
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
    0.622
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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