STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (347 aa)    
Predicted Functional Partners:
selA
L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.983
Deba_1137
COGs: COG0492 Thioredoxin reductase; InterPro IPR000103:IPR013027:IPR005982; KEGG: pth:PTH_1417 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A5D2B9 Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.918
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
    
 0.890
Deba_2879
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795:IPR004161:IPR015190:IPR015191:IPR 011991:IPR009000:IPR009001:IPR005225:IPR004535; KEGG: dal:Dalk_1105 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; SPTR: B8F962 Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu C [...]
 
   
 0.834
Deba_3175
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119:IPR011991; KEGG: dal:Dalk_0925 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Q1K103 Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
 
   
 0.779
Deba_3152
Selenium metabolism protein YedF; InterPro IPR019870:IPR001455; KEGG: dal:Dalk_1678 SirA family protein; SPTR: B8FAT0 SirA family protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family.
 
   
 0.764
Deba_3174
Hydrolase; COGs: COG4087 Soluble P-type ATPase; KEGG: sat:SYN_00624 hydrolase; SPTR: Q2LPK6 Hydrolase.
 
     0.763
Deba_3176
Creatininase; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: sfu:Sfum_0661 creatininase; PFAM: Creatininase; SPTR: A0LG08 Creatininase; PFAM: Creatinine amidohydrolase.
       0.526
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.453
cysS-2
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR005856:IPR002308:IPR001926:IPR009080:IPR 015803:IPR015273:IPR014729:IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: B8FC88 Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
     
 0.424
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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