Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_3175Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119:IPR011991; KEGG: dal:Dalk_0925 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Q1K103 Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family. (299 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.832
Deba_3174
Hydrolase; COGs: COG4087 Soluble P-type ATPase; KEGG: sat:SYN_00624 hydrolase; SPTR: Q2LPK6 Hydrolase.
 
     0.830
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
 
   
 0.819
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.768
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.764
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.748
Deba_1152
COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.670
Deba_3176
Creatininase; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: sfu:Sfum_0661 creatininase; PFAM: Creatininase; SPTR: A0LG08 Creatininase; PFAM: Creatinine amidohydrolase.
 
     0.637
Deba_1550
COGs: COG3264 Small-conductance mechanosensitive channel; InterProIPR000595:IPR018490:IPR011066:IPR010920:IPR 006685:IPR014710; KEGG: mxa:MXAN_2799 mechanosensitive ion channel/cyclic nucleotide-binding domain-containing protein; PFAM: MscS Mechanosensitive ion channel; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: B5II47 Mechanosensitive ion channel/cyclic nucleotide-binding domain protein; PFAM: Mechanosensitive ion channel; Cyclic nucleotide-binding domain.
  
 
 0.590
Deba_1677
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001808:IPR018490:IPR014710:IPR 011991:IPR012318; KEGG: dal:Dalk_0952 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: B8FI88 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
   
 
 0.575
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (18%) [HD]