Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)    
Predicted Functional Partners:
aroK-2
Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 0.996
Deba_3217
Shikimate dehydrogenase substrate binding domain protein; COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR016040:IPR013708:IPR006151; KEGG: dat:HRM2_30830 AroE2; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: C0QKS6 AroE2; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase.
 
 
 0.990
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.898
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
   
 0.889
Deba_3215
Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218:IPR013785; KEGG: adg:Adeg_1912 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: C9R9L3 Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; phospho-2-dehydro-3-deoxyheptonate aldolase.
     
 0.812
Deba_1211
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR001714:IPR000994:IPR000587; KEGG: sfu:Sfum_0169 peptidase M24; PFAM: peptidase M24; creatinase; SPTR: Q1NY97 Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain.
 
  
 0.757
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.727
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
       0.718
Deba_3222
Type I phosphodiesterase/nucleotide pyrophosphatase; COGs: COG3379 conserved hypothetical protein; InterPro IPR017850:IPR002591:IPR017849; KEGG: dvu:DVU0155 type I phosphodiesterase/nucleotide pyrophosphatase family protein; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Q72FQ8 Type I phosphodiesterase/nucleotide pyrophosphatase family protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
       0.718
Deba_1969
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
    0.716
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.