STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Deba_3254Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR016185:IPR011054:IPR005481:IPR005479:IPR 005482:IPR011761:IPR011764:IPR013817:IPR013816; KEGG: dol:Dole_2179 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: A8ZUF1 Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-term [...] (495 aa)    
Predicted Functional Partners:
Deba_3253
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: dol:Dole_2180 propionyl-CoA carboxylase; PFAM: carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: A8ZUF2 Propionyl-CoA carboxylase; PFAM: Carboxyl transferase domain.
 
 0.997
Deba_2144
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
 
 0.996
Deba_1955
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterProIPR014043:IPR016035:IPR016036:IPR001227:IPR 004410; KEGG: dal:Dalk_3440 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: B8FLI2 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.986
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.975
Deba_1368
Conserved carboxylase region; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379:IPR013785; KEGG: dat:HRM2_31800 Pcb; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; SPTR: C0QLF7 Pcb; PFAM: HMGL-like; Conserved carboxylase domain.
  
 
 0.972
Deba_3256
Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR011053:IPR000089:IPR001882; KEGG: dol:Dole_2178 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: A8ZUF0 Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme.
 
  
  0.960
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.952
Deba_0943
2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterProIPR013709:IPR000891:IPR002034:IPR013785:IPR 005675; KEGG: sfu:Sfum_2174 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; SPTR: A0LKA4 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family pro [...]
  
 
 0.952
Deba_1493
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: dal:Dalk_2022 carboxyl transferase; PFAM: carboxyl transferase; SPTR: B8FG38 Carboxyl transferase; PFAM: Carboxyl transferase domain.
 
 0.949
Deba_0881
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762:IPR011763:IPR000438:IPR000022; KEGG: pdi:BDI_0075 propionyl-CoA carboxylase beta chain; PFAM: carboxyl transferase; SPTR: C1SKV2 Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta); PFAM: Carboxyl transferase domain.
 
 0.942
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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