STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_3290Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: rrs:RoseRS_3816 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: A5UZW7 Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (691 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 
 0.901
Deba_0631
Diguanylate phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: pth:PTH_0666 signaling protein; PFAM: EAL domain protein; SMART: EAL domain protein; SPTR: A5D4I7 Hypothetical signaling protein; PFAM: EAL domain.
  
 0.862
Deba_3178
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: hor:Hore_12730 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: B8CXK4 Metal dependent phosphohydrolase; PFAM: HD domain.
 
 0.808
Deba_3301
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: dal:Dalk_3112 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: B8FBP9 Metal dependent phosphohydrolase; PFAM: HD domain; GAF domain.
  
 0.776
Deba_0449
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: dat:HRM2_39120 HD-GYP hydrolase domain family protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C0QBG8 HD-GYP hydrolase domain family protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 
 0.761
Deba_2703
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: dma:DMR_44230 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C4XR34 Putative uncharacterized protein; PFAM: HD domain.
 
 0.754
Deba_2013
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterProIPR001789:IPR003018:IPR003607:IPR006674:IPR 011006; KEGG: sfu:Sfum_3292 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: A0LNG3 Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain [...]
  
 0.697
Deba_2329
COGs: COG4786 Flagellar basal body rod protein; InterProIPR019776:IPR001444:IPR010930:IPR020013:IPR 012836; KEGG: geo:Geob_0627 flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: B9M0F5 Flagellar basal-body rod protein FlgF; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins.
   
   0.683
Deba_3291
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR003594:IPR009082:IPR003018:IPR 013656:IPR003661:IPR005467:IPR004358; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: A9W9X5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF do [...]
  
 
 0.620
Deba_0503
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000644:IPR000160; KEGG: drt:Dret_0176 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: C8WZK3 Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
0.607
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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