Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_3298Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: sfu:Sfum_2382 adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: A0LKW1 Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. (705 aa)    
Predicted Functional Partners:
Deba_3300
Protein of unknown function DUF1058; InterPro IPR010466; KEGG: sfu:Sfum_2380 hypothetical protein; PFAM: protein of unknown function DUF1058; SPTR: A0LKV9 Putative uncharacterized protein; PFAM: Bacterial SH3 domain.
 
     0.943
Deba_3301
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: dal:Dalk_3112 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: B8FBP9 Metal dependent phosphohydrolase; PFAM: HD domain; GAF domain.
 
 
 0.937
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.919
Deba_2303
Putative methyl-accepting chemotaxis sensory transducer; InterPro IPR003660; KEGG: dal:Dalk_2462 protein serine/threonine phosphatase; PFAM: histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: B8FF95 Protein serine/threonine phosphatase; PFAM: HAMP domain.
    
 0.908
Deba_1244
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.903
Deba_0953
MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.
    
  0.902
Deba_0697
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: tai:Taci_0633 anaerobic ribonucleoside-triphosphate reductase; SPTR: D1B9B6 Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
     
  0.900
Deba_1550
COGs: COG3264 Small-conductance mechanosensitive channel; InterProIPR000595:IPR018490:IPR011066:IPR010920:IPR 006685:IPR014710; KEGG: mxa:MXAN_2799 mechanosensitive ion channel/cyclic nucleotide-binding domain-containing protein; PFAM: MscS Mechanosensitive ion channel; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: B5II47 Mechanosensitive ion channel/cyclic nucleotide-binding domain protein; PFAM: Mechanosensitive ion channel; Cyclic nucleotide-binding domain.
  
 0.894
Deba_3302
COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: sat:SYN_00175 metal-dependent hydrolase; SPTR: Q2LQ10 Metal-dependent hydrolase.
 
     0.881
Deba_3299
Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: sfu:Sfum_2381 peptidase M48, Ste24p; PFAM: peptidase M48 Ste24p; SPTR: A0LKW0 Peptidase M48, Ste24p; PFAM: Peptidase family M48.
 
     0.863
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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