STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_3302COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: sat:SYN_00175 metal-dependent hydrolase; SPTR: Q2LQ10 Metal-dependent hydrolase. (274 aa)    
Predicted Functional Partners:
Deba_3298
Adenylate/guanylate cyclase with Chase sensor; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: sfu:Sfum_2382 adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: A0LKW1 Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain.
 
     0.896
Deba_3301
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: dal:Dalk_3112 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: B8FBP9 Metal dependent phosphohydrolase; PFAM: HD domain; GAF domain.
 
     0.844
Deba_3299
Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: sfu:Sfum_2381 peptidase M48, Ste24p; PFAM: peptidase M48 Ste24p; SPTR: A0LKW0 Peptidase M48, Ste24p; PFAM: Peptidase family M48.
       0.664
Deba_3300
Protein of unknown function DUF1058; InterPro IPR010466; KEGG: sfu:Sfum_2380 hypothetical protein; PFAM: protein of unknown function DUF1058; SPTR: A0LKV9 Putative uncharacterized protein; PFAM: Bacterial SH3 domain.
       0.664
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.597
Deba_3303
ABC-2 type transporter; COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease component; InterPro IPR013525:IPR000412; KEGG: mxa:MXAN_4623 O-antigen ABC exporter, permease protein; PFAM: ABC-2 type transporter; SPTR: Q094Z0 O-antigen export system permease protein RfbA; PFAM: ABC-2 type transporter.
     
 0.540
Deba_2255
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594:IPR011006:IPR009082:IPR004358:IPR 005467:IPR001789:IPR000700:IPR003660:IPR001610:IPR003661:I PR013767:IPR000014; KEGG: dal:Dalk_3402 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAC repeat-containing protein; response [...]
 
  
 0.468
Deba_0019
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR011006:IPR009082:IPR019825:I PR004358; KEGG: dal:Dalk_2518 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; response regulator recei [...]
 
     0.410
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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