STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crgAProtein of unknown function UPF0233; Involved in cell division; Belongs to the CrgA family. (87 aa)    
Predicted Functional Partners:
ADL43667.1
KEGG: stp:Strop_0046 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase.
   
 
 0.783
ADL47984.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 
 0.769
ADL47979.1
DivIVA domain; KEGG: stp:Strop_3206 DivIVA family protein; TIGRFAM: DivIVA domain; PFAM: DivIVA family protein.
  
   
 0.741
ADL47991.1
KEGG: saq:Sare_3444 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain.
   
 
 0.731
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.728
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
      
 0.687
glnE
GlnD PII-uridylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein P [...]
      
 0.612
ADL43674.1
PFAM: protein of unknown function DUF881; KEGG: saq:Sare_0057 hypothetical protein.
       0.597
ADL43664.1
KEGG: stp:Strop_0043 FHA domain-containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
  
 0.584
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
      
 0.584
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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