STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL43697.1PFAM: regulatory protein MerR; Protein phosphatase 2C-like; KEGG: stp:Strop_2316 regulatory protein, MerR; SMART: regulatory protein MerR; protein phosphatase 2C domain protein. (350 aa)    
Predicted Functional Partners:
ADL43669.1
Serine/threonine-protein kinase-like domain; KEGG: saq:Sare_0053 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: PASTA domain containing protein.
 
 
 0.950
ADL48022.1
KEGG: stp:Strop_3253 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: PASTA domain containing protein.
 
 
 0.950
ADL44296.1
Hypothetical protein; KEGG: tca:656238 similar to CG1105-PA.
  
 
 0.922
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.914
dnaJ-2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.914
ADL48867.1
KEGG: saq:Sare_1580 putative plasmid replication initiator protein.
  
 
 0.914
ADL49531.1
KEGG: sro:Sros_4024 heat shock protein DnaJ domain-containing protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.
  
 
 0.914
ADL46186.1
PFAM: Transketolase central region; Transketolase domain-containing protein; biotin/lipoyl attachment domain-containing protein; catalytic domain-containing protein of components of various dehydrogenase complexes; KEGG: sro:Sros_2206 pyruvate dehydrogenase (acetyl-transferring); Belongs to the 2-oxoacid dehydrogenase family.
   
 0.872
ADL45894.1
PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: stp:Strop_1870 Fmu (Sun) domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.854
ADL44373.1
Manually curated; PFAM: Serine/threonine-protein kinase-like domain; KEGG: saq:Sare_0775 serine/threonine protein kinase; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain.
 
 
 0.831
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.