STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLKEGG: stp:Strop_4100 glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (445 aa)    
Predicted Functional Partners:
ADL49145.1
Porphobilinogen synthase; KEGG: saq:Sare_0429 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.997
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.995
ADL43904.1
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: saq:Sare_4518 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
  
  
 0.987
ADL43903.1
KEGG: saq:Sare_4519 phosphoglycerate mutase; manually curated; PFAM: Phosphoglycerate mutase.
  
    0.981
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.962
ADL43907.1
KEGG: saq:Sare_4515 cytochrome c assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein.
 
  
 0.960
ADL43906.1
KEGG: stp:Strop_4096 ResB family protein.
  
  
 0.931
ADL47419.1
Beta-ketoacyl synthase; KEGG: cai:Caci_2598 KR domain protein; PFAM: Beta-ketoacyl synthase; KR domain protein; Enoyl-CoA hydratase/isomerase; phosphopantetheine-binding; Methyltransferase type 12; aromatic amino acid beta-eliminating lyase/threonine aldolase; alpha/beta hydrolase fold; SMART: Polyketide synthase, beta-ketoacyl synthase region; Polyketide synthase, phosphopantetheine-binding; Polyketide synthase/Fatty acid synthase, KR.
     
 0.910
ADL43905.1
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: stp:Strop_4097 cytochrome c biogenesis protein, transmembrane region.
  
  
 0.903
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.891
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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