STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL43996.1KEGG: saq:Sare_4433 hypothetical protein. (248 aa)    
Predicted Functional Partners:
ADL49184.1
PFAM: Protein of unknown function DUF2596; KEGG: stp:Strop_0332 hypothetical protein.
  
     0.769
ADL43703.1
PFAM: acyl-CoA dehydrogenase domain-containing protein; Acyl-CoA dehydrogenase, N-terminal, bacteria; KEGG: stp:Strop_0089 acyl-CoA dehydrogenase domain-containing protein.
  
     0.651
ADL49221.1
PFAM: protein of unknown function DUF1416; KEGG: saq:Sare_0341 hypothetical protein.
  
     0.642
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.602
ADL45908.1
KEGG: saq:Sare_1874 hypothetical protein.
  
     0.600
ADL48047.1
Hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.596
ADL49427.1
KEGG: saq:Sare_4793 anion-transporting ATPase.
  
     0.581
ADL48760.1
TIGRFAM: anti-sigma factor; KEGG: stp:Strop_3713 hypothetical protein.
  
     0.556
ADL43997.1
TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: saq:Sare_4432 HAD family hydrolase.
      
 0.544
ADL43676.1
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: saq:Sare_0059 hypothetical protein.
  
     0.540
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
Server load: medium (48%) [HD]