STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL44025.1PFAM: PSP1 domain protein; KEGG: saq:Sare_4399 PSP1 domain-containing protein. (280 aa)    
Predicted Functional Partners:
rny
YmdA/YtgF protein; Endoribonuclease that initiates mRNA decay.
 
  
 0.780
ADL44021.1
TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: AAA ATPase central domain protein; KEGG: saq:Sare_4403 DNA polymerase III, delta prime subunit; SMART: AAA ATPase.
  
   0.503
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.447
ADL44022.1
Uncharacterized protein family UPF0133; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
       0.430
ADL44023.1
KEGG: saq:Sare_4401 hypothetical protein.
       0.430
ADL44024.1
KEGG: saq:Sare_4400 hypothetical protein.
       0.430
ADL48788.1
KEGG: saq:Sare_4113 hypothetical protein.
  
     0.424
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.419
ADL48328.1
PFAM: Antibiotic biosynthesis monooxygenase; KEGG: stp:Strop_3435 antibiotic biosynthesis monooxygenase.
  
     0.403
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.