STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (499 aa)    
Predicted Functional Partners:
ADL46455.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.979
ADL44482.1
TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; KEGG: saq:Sare_0855 cystathionine beta-synthase; SMART: CBS domain containing protein.
 
 0.940
ADL44490.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: saq:Sare_0863 cystathionine gamma-synthase.
  
 0.923
ADL45300.1
KEGG: mjl:Mjls_0824 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase.
     
 0.904
ADL49559.1
Manually curated; TIGRFAM: DNA-cytosine methyltransferase; KEGG: mva:Mvan_1093 DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase.
     
 0.904
ADL49616.1
PFAM: C-5 cytosine-specific DNA methylase; KEGG: sna:Snas_4216 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.904
ADL46610.1
PFAM: aminotransferase class I and II; KEGG: saq:Sare_2784 aminotransferase class I and II.
     
  0.900
ADL43919.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_4089 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 0.852
ADL44900.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: stp:Strop_1267 cystathionine gamma-lyase.
  
 0.846
ADL48666.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; KEGG: saq:Sare_4033 homoserine dehydrogenase.
   
 
 0.824
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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