STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL45565.1KEGG: kfl:Kfla_2239 D-aspartate oxidase; PFAM: FAD dependent oxidoreductase. (317 aa)    
Predicted Functional Partners:
ADL47329.1
PFAM: FAD dependent oxidoreductase; KEGG: saq:Sare_2137 FAD dependent oxidoreductase.
  
  
  0.921
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.917
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.907
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.907
ADL48024.1
KEGG: saq:Sare_3482 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase.
     
 0.903
ADL46215.1
Cephalosporin-C deacetylase; KEGG: sgr:SGR_6428 putative acetyl xylan esterase; PFAM: Acetyl xylan esterase.
     
  0.900
ADL46920.1
Cephalosporin-C deacetylase; KEGG: cmi:CMM_0227 putative acetyl xylan esterase; PFAM: Acetyl xylan esterase.
     
  0.900
ADL47439.1
Cephalosporin-C deacetylase; KEGG: sma:SAV_1457 acetyl xylan esterase; PFAM: Acetyl xylan esterase.
     
  0.900
ADL43894.1
PFAM: FAD linked oxidase domain protein; KEGG: FAD linked oxidase domain-containing protein.
     
 0.802
ADL49249.1
PFAM: FAD linked oxidase domain protein; KEGG: stp:Strop_0273 FAD linked oxidase domain-containing protein.
     
 0.802
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
Server load: low (34%) [HD]