STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL45772.1KEGG: stp:Strop_1767 hypothetical protein. (329 aa)    
Predicted Functional Partners:
ADL48795.1
Manually curated; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: saq:Sare_4120 UvrD/REP helicase; SMART: HRDC domain protein.
    
 
 0.920
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.904
ADL45616.1
PFAM: DNA gyrase subunit B domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; KEGG: saq:Sare_1674 DNA gyrase subunit B; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
   
 
 0.904
ADL48501.1
Hypothetical protein; KEGG: DNA gyrase, B subunit.
   
 
 0.904
ADL45770.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: saq:Sare_1751 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.842
ADL45771.1
PFAM: glycosyl transferase family 9; KEGG: stp:Strop_1766 glycosyl transferase family protein.
       0.790
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.759
ADL45766.1
PFAM: glycosyl transferase group 1; KEGG: saq:Sare_1747 hypothetical protein.
 
 
 
 0.718
ADL45765.1
KEGG: stp:Strop_1760 HAD superfamily hydrolase; TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; histidinol-phosphate phosphatase family protein; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: glycosyl transferase family 9; Haloacid dehalogenase domain protein hydrolase.
   
 
 0.711
ADL45769.1
Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
     0.680
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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