STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL45831.1KEGG: saq:Sare_1797 3-hydroxybutyrate dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR. (260 aa)    
Predicted Functional Partners:
ADL45830.1
GAF domain protein; KEGG: saq:Sare_1796 transcriptional regulator, CdaR; PFAM: GAF domain protein; SMART: GAF domain protein.
 
     0.944
ADL44508.1
KEGG: saq:Sare_0879 acetoacetyl-CoA synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase.
    
 0.902
ADL43645.1
PFAM: pyruvate carboxyltransferase; KEGG: saq:Sare_0032 pyruvate carboxyltransferase.
     
  0.900
ADL47283.1
PFAM: pyruvate carboxyltransferase; KEGG: fre:Franean1_3719 pyruvate carboxyltransferase.
     
  0.900
ADL47419.1
Beta-ketoacyl synthase; KEGG: cai:Caci_2598 KR domain protein; PFAM: Beta-ketoacyl synthase; KR domain protein; Enoyl-CoA hydratase/isomerase; phosphopantetheine-binding; Methyltransferase type 12; aromatic amino acid beta-eliminating lyase/threonine aldolase; alpha/beta hydrolase fold; SMART: Polyketide synthase, beta-ketoacyl synthase region; Polyketide synthase, phosphopantetheine-binding; Polyketide synthase/Fatty acid synthase, KR.
  
 0.701
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.537
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.537
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
     
 0.537
ADL47406.1
PfaD family protein; KEGG: bay:RBAM_022080 DfnA; TIGRFAM: PfaD family protein; malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; 2-nitropropane dioxygenase NPD.
  
 
 0.499
ADL47407.1
KEGG: cai:Caci_2592 amino acid adenylation domain protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Beta-ketoacyl synthase; nitroreductase; phosphopantetheine-binding; Non-ribosomal peptide synthetase.
  
 
 0.497
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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