STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL46386.1PFAM: transcriptional activator domain; transcriptional regulator domain-containing protein; NB-ARC domain protein; Tetratricopeptide TPR_1 repeat-containing protein; KEGG: cai:Caci_5051 transcriptional regulator, SARP family. (938 aa)    
Predicted Functional Partners:
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: saq:Sare_1880 phenylalanyl-tRNA synthetase, beta subunit.
  
    0.666
ADL47214.1
TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation protein E; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: kfl:Kfla_4457 multi-sensor signal transduction histidine kinase; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; protein phosphatase 2C domain protein.
  
 
 0.654
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.631
ADL47419.1
Beta-ketoacyl synthase; KEGG: cai:Caci_2598 KR domain protein; PFAM: Beta-ketoacyl synthase; KR domain protein; Enoyl-CoA hydratase/isomerase; phosphopantetheine-binding; Methyltransferase type 12; aromatic amino acid beta-eliminating lyase/threonine aldolase; alpha/beta hydrolase fold; SMART: Polyketide synthase, beta-ketoacyl synthase region; Polyketide synthase, phosphopantetheine-binding; Polyketide synthase/Fatty acid synthase, KR.
  
 
 0.625
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.591
ADL46248.1
Alanine--tRNA ligase; KEGG: sco:SCO7600 alanyl tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc-like.
   
 0.591
ADL46895.1
WD40 repeat, subgroup; KEGG: sro:Sros_2975 WD40 repeatdomain-containing protein-like protein; PFAM: WD40 repeat, subgroup; pentapeptide repeat protein; SMART: TIR protein; WD-40 repeat-containing protein.
  
 0.584
ADL43641.1
PFAM: ATP-binding region ATPase domain protein; KEGG: tcu:Tcur_4208 ATP-binding region ATPase domain protein.
   
 0.569
htpG
Heat shock protein Hsp90-like; Molecular chaperone. Has ATPase activity.
   
 0.569
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.564
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.