STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL46403.1Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (667 aa)    
Predicted Functional Partners:
ADL48078.1
Cytochrome-c oxidase; Manually curated; KEGG: saq:Sare_3527 cytochrome c oxidase subunit III; PFAM: cytochrome c oxidase subunit III.
 0.999
ADL48084.1
KEGG: stp:Strop_3300 cytochrome c oxidase, subunit II; TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II.
 
 0.999
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.997
ADL48075.1
PFAM: Cytochrome b/b6 domain; KEGG: stp:Strop_3292 cytochrome b/b6 domain-containing protein.
 
 
 0.996
ADL48076.1
PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: saq:Sare_3525 Rieske (2Fe-2S) domain-containing protein.
 
 
 0.986
ADL48077.1
PFAM: cytochrome c class I; KEGG: saq:Sare_3526 cytochrome c class I.
 
 
 0.978
ADL48083.1
Cytochrome-c oxidase; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
 
 
 0.972
ADL44974.1
KEGG: stp:Strop_1329 hypothetical protein.
    
   0.935
ADL49065.1
KEGG: saq:Sare_0472 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
 
 0.923
ADL43974.1
KEGG: stp:Strop_4053 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
 
 0.920
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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