STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL46721.1TIGRFAM: pyridoxal kinase; KEGG: saq:Sare_2647 pyridoxamine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Belongs to the pyridoxine kinase family. (283 aa)    
Predicted Functional Partners:
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
    
 0.921
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 0.918
pdxT
SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.918
ADL43705.1
PFAM: aldo/keto reductase; KEGG: cai:Caci_5769 aldo/keto reductase.
    
  0.901
ADL45472.1
PFAM: aldo/keto reductase; KEGG: sro:Sros_5279 putative oxidoreductase.
    
  0.901
ADL47917.1
PFAM: aldo/keto reductase; KEGG: nfa:nfa3270 putative oxidoreductase.
    
  0.901
ADL46724.1
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: scb:SCAB_7511 hypothetical protein.
    
  0.751
ADL47982.1
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.672
ADL46722.1
KEGG: nml:Namu_2902 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.
       0.526
ADL46723.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: nml:Namu_2901 glyoxalase/bleomycin resistance protein/dioxygenase.
       0.526
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
Server load: medium (52%) [HD]