STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL46736.1PFAM: Chorismate binding-like; KEGG: saq:Sare_2513 chorismate binding-like protein. (397 aa)    
Predicted Functional Partners:
ADL43671.1
KEGG: stp:Strop_0049 para-aminobenzoate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
 0.999
ADL46126.1
KEGG: cai:Caci_3668 glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.985
trpC
KEGG: stp:Strop_3172 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.980
ADL49213.1
PFAM: aminotransferase class IV; KEGG: saq:Sare_0374 aminotransferase class IV.
 
 
 0.951
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.946
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.941
ADL47419.1
Beta-ketoacyl synthase; KEGG: cai:Caci_2598 KR domain protein; PFAM: Beta-ketoacyl synthase; KR domain protein; Enoyl-CoA hydratase/isomerase; phosphopantetheine-binding; Methyltransferase type 12; aromatic amino acid beta-eliminating lyase/threonine aldolase; alpha/beta hydrolase fold; SMART: Polyketide synthase, beta-ketoacyl synthase region; Polyketide synthase, phosphopantetheine-binding; Polyketide synthase/Fatty acid synthase, KR.
  
  
 0.933
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.914
ADL47407.1
KEGG: cai:Caci_2592 amino acid adenylation domain protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Beta-ketoacyl synthase; nitroreductase; phosphopantetheine-binding; Non-ribosomal peptide synthetase.
  
  
 0.880
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.