STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL46887.1PFAM: fatty acid hydroxylase; KEGG: nfa:nfa16290 hypothetical protein. (275 aa)    
Predicted Functional Partners:
ADL43813.1
Phytoene synthase; KEGG: saq:Sare_4931 squalene/phytoene synthase; PFAM: Squalene/phytoene synthase.
  
 
 0.929
ADL46888.1
PFAM: YhhN family protein; KEGG: sna:Snas_5175 YhhN family protein.
 
     0.868
ADL46886.1
Regulatory protein GntR HTH; KEGG: nfa:nfa16280 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; GntR domain protein.
 
     0.815
ADL47239.1
PFAM: Prenyltransferase/squalene oxidase; KEGG: sen:SACE_4648 prenyltransferase/squalene oxidase.
   
 
 0.784
ADL47802.1
PFAM: Prenyltransferase/squalene oxidase; KEGG: saq:Sare_1288 hypothetical protein.
   
 
 0.784
smpB-2
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.773
ADL46890.1
KEGG: sen:SACE_6984 hypothetical protein.
   
 
 0.659
ADL46004.1
PFAM: Beta-ketoacyl synthase; Acyl transferase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; KEGG: sma:SAV_419 modular polyketide synthase.
  
 
 0.648
ADL47416.1
PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: cai:Caci_2601 hydroxymethylglutaryl-coenzyme A synthase domain protein.
   
 
 0.580
ADL47427.1
KEGG: cai:Caci_2595 hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain protein; Hydroxymethylglutaryl-coenzyme A synthase domain.
   
 
 0.580
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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