STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL46976.1PFAM: DNA primase small subunit; KEGG: saq:Sare_2236 DNA primase small subunit. (326 aa)    
Predicted Functional Partners:
ADL44051.1
KEGG: saq:Sare_4352 DNA polymerase LigD ligase region; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein.
   
 0.977
ADL44706.1
KEGG: cai:Caci_5248 DNA polymerase LigD, ligase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase.
   
 0.977
ADL45201.1
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: saq:Sare_1489 ATP-dependent DNA ligase.
   
 0.919
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.885
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
   
 0.741
ADL46977.1
KEGG: stp:Strop_2879 hypothetical protein.
       0.664
ADL46978.1
KEGG: stp:Strop_2880 VWA containing CoxE family protein; PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor type A.
       0.664
ADL46979.1
KEGG: stp:Strop_2881 hypothetical protein.
       0.664
ADL46980.1
KEGG: stp:Strop_2882 ATPase; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
       0.664
ADL46981.1
KEGG: stp:Strop_2883 WGR domain-containing protein; PFAM: WGR domain-containing protein; SMART: WGR domain-containing protein.
       0.664
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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