STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL48174.1PFAM: flavoprotein; KEGG: saq:Sare_3598 hypothetical protein. (193 aa)    
Predicted Functional Partners:
ADL48175.1
KEGG: stp:Strop_3359 helix-turn-helix domain-containing protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
 
    0.857
ADL48173.1
PFAM: protein of unknown function DUF34; KEGG: saq:Sare_3597 hypothetical protein.
       0.687
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
  
 0.644
ADL47930.1
KEGG: saq:Sare_3392 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein.
     
 0.639
ADL48172.1
PFAM: protein of unknown function DUF164; KEGG: saq:Sare_3596 hypothetical protein.
       0.639
ADL48176.1
PFAM: Bifunctional DNA primase/polymerase; KEGG: stp:Strop_3360 hypothetical protein.
 
     0.633
ADL48171.1
PFAM: Phosphoglycerate mutase; ribonuclease H; KEGG: saq:Sare_3595 phosphoglycerate mutase.
  
    0.613
priA
Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
    0.562
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.509
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
   
 
 0.486
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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