STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL48213.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (914 aa)    
Predicted Functional Partners:
ADL48114.1
KEGG: saq:Sare_3551 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerization region.
  
 
 0.953
ADL47915.1
TIGRFAM: pyruvate kinase; KEGG: saq:Sare_3385 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.927
ADL44217.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: stp:Strop_0699 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
     
 0.925
ADL44833.1
Transketolase domain-containing protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 
0.920
ADL43718.1
TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; KEGG: saq:Sare_0109 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component.
    
 0.916
ADL46974.1
TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; KEGG: saq:Sare_2238 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component.
    
 0.916
ADL48586.1
Pyruvate dehydrogenase (acetyl-transferring); KEGG: sgr:SGR_3765 putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit; PFAM: dehydrogenase E1 component.
    
 0.916
ADL45109.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: saq:Sare_1406 malate dehydrogenase.
    
 0.912
ADL48739.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: stp:Strop_3695 malate dehydrogenase.
    
 0.912
ADL44216.1
2-oxoglutarate synthase; KEGG: saq:Sare_0645 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
     
 0.908
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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